Iran has shown a sincere interest in solving the Jewish problem in the Middle East before. Among other Iran's efforts are support of
- Hezbollah (Shiite, southern Lebanon
- Hamas (Sunni, Palestine/Gaza)
- Islamic Jihad ((I haven't learned which flavor of Islam), Palestine/Lebanon)
Since the conference is unlikely to swear death to Israel, death to the Great Satan America, I suppose the Ayatollah Khamenei's attitude is understandable. I could be wrong, but considering Iran's track record and the position of Khamenei's subordinant Ahmadinejad on the destruction of Israel, I don't think so.
Related posts, on Individuals and the War on Terror.